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Natural Selection and Antibiotic-Resistant Bacteria (Developed by SEPUP)

kit #904S

Why it is important to take an antibiotic as prescribed? Students model the effects of antibiotics on the population of disease-causing bacteria during an infection. During the simulation, some groups complete the full course of antibiotics, while others miss doses. They then graph populations of more-resistant and less-resistant bacteria. Students observe the selection of more-resistant bacteria that can take place if antibiotic treatment is intermittent or discontinued prematurely. Through this activity, student learn why it's important to take "the full course" of antibiotics.


  • Creating models is one way to understand and communicate scientific information
  • Graphing data can reveal patterns that are not apparent from data tables
  • Most infectious diseases are caused by microbes
  • The human body has natural defenses against infectious diseases
  • Antibiotics are effective against many bacterial infections, but not against viral infections
  • Antibiotics can be effective against bacterial infections only if the entire course is completed as directed

Content List in Natural Selection and Antibiotic-Resistant Bacteria (Developed by SEPUP) is as follows:

Quantity Description
1 Teacher’s Guide with MSDS
32 Student Worksheets and Guides
320 Blue disks
240 Yellow disks
240 Red disks
16 Number cubes
1 Transparency: Bacteria Graph Sample 1
1 Transparency: Bacteria Graph Sample2
32 Bacteria Graphs
Number of students
Number of groups
Maximum 16 groups per period

To complete this kit requires one to two ~50-minute class periods.

Title Item # Price Quantity
Natural Selection and Antibiotic-Resistant Bacteria (Developed by SEPUP) 904S $83.85